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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPM1J All Species: 13.03
Human Site: S221 Identified Species: 26.06
UniProt: Q5JR12 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5JR12 NP_005158.5 505 54834 S221 L G P Q S C W S S Q K E V S H
Chimpanzee Pan troglodytes XP_513628 505 54871 S221 L G P Q S C W S S Q K E V T H
Rhesus Macaque Macaca mulatta XP_001096598 450 48605 D206 P T T P G T P D S S D P S H L
Dog Lupus familis XP_540335 509 54913 S225 V G P Q S C W S S Q K E V T H
Cat Felis silvestris
Mouse Mus musculus Q149T7 507 55531 S222 V S P Q S C W S P Q K E V T H
Rat Rattus norvegicus Q641Y6 504 55192 P220 V S P Q S W S P Q K E V T H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507685 606 67811 G213 R N Q R M L G G C C A L V V V
Chicken Gallus gallus XP_418000 495 54949 H211 N D A L P R F H L E K A V S H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q05AL2 516 56543 N246 L V V G A I E N A F K E M D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608468 651 72868 F217 G A L E S A F F N M D S L I A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798783 601 66691 F300 Q R P N K W P F N E K E V S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49598 399 43332 E155 H V A E K C R E R L H D I V K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 85.5 93.1 N.A. 88.3 88.3 N.A. 56.1 68.5 N.A. 47.2 N.A. 30.8 N.A. N.A. 36.1
Protein Similarity: 100 100 86.7 96.2 N.A. 91.3 90.6 N.A. 63.2 77 N.A. 62 N.A. 45 N.A. N.A. 51.2
P-Site Identity: 100 93.3 6.6 86.6 N.A. 73.3 20 N.A. 6.6 26.6 N.A. 20 N.A. 6.6 N.A. N.A. 33.3
P-Site Similarity: 100 100 6.6 100 N.A. 86.6 40 N.A. 13.3 40 N.A. 46.6 N.A. 33.3 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 22.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 9 9 0 0 9 0 9 9 0 0 17 % A
% Cys: 0 0 0 0 0 42 0 0 9 9 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 9 0 0 17 9 0 9 9 % D
% Glu: 0 0 0 17 0 0 9 9 0 17 9 50 0 0 0 % E
% Phe: 0 0 0 0 0 0 17 17 0 9 0 0 0 0 0 % F
% Gly: 9 25 0 9 9 0 9 9 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 9 0 0 9 0 0 17 42 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 9 9 0 % I
% Lys: 0 0 0 0 17 0 0 0 0 9 59 0 0 0 9 % K
% Leu: 25 0 9 9 0 9 0 0 9 9 0 9 9 0 9 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 9 0 0 % M
% Asn: 9 9 0 9 0 0 0 9 17 0 0 0 0 0 0 % N
% Pro: 9 0 50 9 9 0 17 9 9 0 0 9 0 0 0 % P
% Gln: 9 0 9 42 0 0 0 0 9 34 0 0 0 0 0 % Q
% Arg: 9 9 0 9 0 9 9 0 9 0 0 0 0 0 0 % R
% Ser: 0 17 0 0 50 0 9 34 34 9 0 9 9 25 0 % S
% Thr: 0 9 9 0 0 9 0 0 0 0 0 0 9 25 0 % T
% Val: 25 17 9 0 0 0 0 0 0 0 0 9 59 17 17 % V
% Trp: 0 0 0 0 0 17 34 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _